Cinnamic acids and derivatives
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 1 ML
p-Coumaric Acid Ethyl Ester, also known as Ethyl (E)-p-hydroxycinnamate or Ethyl trans-4-hydroxycinnamate, is a reversible, non-competitive inhibitor of tyrosinase. It quenches the enzyme's intrinsic fluorescence and alters the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain, without binding to the copper ion. This compound finds application in the development of various products, including medicines, cosmetics, and fruit preservation products that utilize pollen.
- Non-competitive and reversible tyrosinase inhibitor.
- Changes L-tyrosine binding affinity through conformational changes in tyrosinase's catalytic domain.
- Does not bind to the copper ion of the enzyme.
- Applicable in developing medicines.
- Used in cosmetic formulations.
- Utilized in fruit preservation products.
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.07% | 274.25 | 100 MG
Ferulic acid 4-O-sulfate, also known as Ferulic acid 4-sulfate, is a metabolite of Ferulic acid that has been observed to relax arteries and decrease blood pressure in mice.
- In vitro: This compound, at concentrations ranging from 0.1 to 30 μM, elicited significant concentration-dependent relaxations in the aorta, femoral, and saphenous arteries of mice.
- In vivo: When administered intravenously to male Swiss mice at dosages of 16.13 and 161.3 μg/kg, ferulic acid 4-O-sulfate demonstrated the ability to relax arteries and lower blood pressure, with a significant decrease in mean arterial pressure (MAP) observed immediately post-injection.
eMolecules 117113-98-1 | 4-(4-Fluorobenzyloxy)benzyl alcohol | Oakwood Chemical | MFCD00173648 | 232.254 | C14H13FO2 | 98.000 | OCc1ccc(OCc2ccc(F)cc2)cc1 | 1g | 537669244
4-(4-Fluorobenzyloxy)benzyl alcohol | Oakwood Chemical | 117113-98-1 | MFCD00173648 | 232.254 | C14H13FO2 | 98.000 | OCc1ccc(OCc2ccc(F)cc2)cc1 | 1g | 537669244
Medchemexpress LLC cis-p-Coumaric acid | 4501-31-9 | 164.16 | 5 MG
cis-p-Coumaric acid, also known as cis-4-Hydroxycinnamic acid, is the cis-form of p-Coumaric acid. This compound is found in higher concentrations in viable groundnut seeds compared to non-viable ones.
- Exhibits oral activity.
- Inhibits cell proliferation.
- Promotes apoptosis.
Medchemexpress LLC 3,4-Dimethoxycinnamic acid | 2316-26-9 | 208.21 | 5 G
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. It exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway. Anti-apoptotic effects.
- Extracted and purified from Securidaca inappendiculata Hassk.
- Exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway.
- Anti-apoptotic effects.
Medchemexpress LLC 3-Methylcinnamic acid | 3029-79-6 | 99.77% | C10H10O2 | 5 G
3-Methylcinnamic acid is a drug intermediate utilized in the synthesis of various active compounds. This product is strictly for research use only and is not intended for patient administration. Careful handling and storage are recommended to maintain product integrity and safety.
- Store powder at -20°C for up to 3 years or at 4°C for 2 years.
- When in solvent, store at -80°C for 6 months or at -20°C for 1 month.
- Avoid breathing dust, fume, gas, mist, vapors, or spray.
- Wash hands thoroughly after handling.
- Use only outdoors or in a well-ventilated area.
- Wear appropriate protective equipment including gloves, clothing, and eye/face protection.
- May cause irritation to skin, eyes, and respiratory tract.
eMolecules 845823-26-9 | 2'-(3-Fluorobenzyloxy)acetophenone | Oakwood Chemical | MFCD06411645 | 244.265 | C15H13FO2 | 99.000 | CC(=O)c1ccccc1OCc1cccc(F)c1 | 1g | 537680623
2'-(3-Fluorobenzyloxy)acetophenone | Oakwood Chemical | 845823-26-9 | MFCD06411645 | 244.265 | C15H13FO2 | 99.000 | CC(=O)c1ccccc1OCc1cccc(F)c1 | 1g | 537680623
Chem-Impex International, Inc. trans-4-Bromocinnamic acid | MFCD00004394 | 25G
trans-4-Bromocinnamic acid, MFCD00004394, 25G
Medchemexpress LLC p-Hydroxycinnamic acid | 7400-08-0 | 10 G
p-Hydroxycinnamic acid is a chemical compound (CAS No. 7400-08-0) primarily utilized as a laboratory chemical and in the manufacture of other substances. With a molecular formula of C9H8O3 and a molecular weight of 164.16, this white to off-white solid is stable under recommended storage conditions and is intended for research use only.
- Appears as a white to off-white solid
- Purity of 99.94% by HPLC
- Structure consistent with ¹H NMR spectrum
- Stable under recommended storage conditions
- Melting point ranges from 212-214°C
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 2 years or -20°C for 1 year
- Requires careful handling to avoid skin, eye, and respiratory irritation
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | MFCD00004379 | 98.71% | 164.16 | 100 MG
2-Hydroxycinnamic acid (Standard) serves as the analytical standard for 2-Hydroxycinnamic acid, intended for research and analytical applications. It is a phenolic acid possessing antimicrobial and antioxidant properties. This analytical standard grade compound is commonly employed in qualitative, quantitative, and methodological research experiments, including HPLC, GC, and MS.
- Demonstrates antimicrobial activity against *Staphylococcus aureus* without susceptibility to drug resistance.
- Exhibits inhibitory effects on HIV/SARS-CoV S pseudovirus infection, with an IC50 of 0.3 mM.
- Possesses neuroprotective activity.
- Possesses antitumor activity.
Medchemexpress LLC (E)-m-Coumaric acid | 14755-02-3 | 1 ML
(E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an aromatic acid highly abundant in food that acts as an antioxidant. It is categorized as an endogenous and microbial metabolite, targeting metabolic enzyme/protease pathways, and is intended for research use only.
- Aromatic acid highly abundant in food
- Acts as an antioxidant
- Categorized as an endogenous metabolite
- Categorized as a microbial metabolite
- Targets metabolic enzyme/protease pathways
- Purity of 99.74%
- Appearance as an off-white to yellow solid
- Molecular formula C9H8O3
- Molecular weight 164.16
- Solubility in DMSO: 100 mg/mL
- Recommended storage at 4°C, protected from light
Apexbio Technology LLC BIBF 1202 894783-71-2 10mg
BIBF 1202 (CAS 894783-71-2) is a carboxylate metabolite derivative of BIBF 1120 characterized as a selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2) kinase In biochemical assays BIBF 1202 demonstrates inhibitory activity against VEGFR2 kinase with an IC50 of 62 nM This compound is frequently employed in studies investigating the regulation of the VEGFR2 signaling pathway and its role in endothelial cell function Additionally BIBF 1202 is utilized in preclinical models related to tumor angiogenesis and associated pharmacological research
Medchemexpress LLC p-Coumaric acid-13C3 | 1261170-80-2 | 167.14 | 500 UG
p-Coumaric acid-13C3 is the 13C-labeled p-Coumaric acid, an abundant isomer of cinnamic acid known for its antitumor and anti-mutagenic activities.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Purity of 99.12%.
- Appears as a solid, white to off-white.
![Research Products International Corp Trans-Cinnamic Acid [B-Phenylacrylic acid], 25 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-C34400-25.0.JPG-250.jpg)
Research Products International Corp Trans-Cinnamic Acid [B-Phenylacrylic acid], 25 Grams
Auxin like growth regulator.